Yog tias cov menyuam muaj kev loj hlob ntau dhau lawm los ntawm kev ceev nrawm, muaj teeb meem kev sib deev, ntau cov kab mob, ces cov niam txiv yuav tsum nrhiav kev pab tsim nyog. Thaum tsis muaj cov tsos mob zoo li no, feem ntau, tsis tas txhawj txog kev loj hlob ntawm cov menyuam yaus.
Kev tswjfwm kev cai ntawm menyuam yaus txoj kev loj hlob
Niaj hnub no, cov me nyuam feem ntau muaj kev tswj kev cai ntawm kev loj hlob, tshwj tsis yog cov neeg muaj kab mob hauv siab. Nyob rau hauv cov menyuam yaus lub sijhawm pubertal los txog thaum ntxov, qhov loj hlob thiab kev loj hlob ntawm cov pob txha yog ceev. Cov neeg siab ncaj cov neeg muaj feem cuam tshuam, lawv tsis raug kev txom nyem los ntawm kev muaj zog ntawm kev nkag siab.
Txoj kev loj hlob tuaj yeem ua rau kom hnyav tshaj qhov hnyav hauv lub hnub nyoog npaj ua ntej, tab sis qhov no yog qhov tshwm sim ib ntus. Hauv qhov no, cov me nyuam loj hlob, tab sis tsis giants.
Cov me nyuam Gigantism
Yog hais tias tus me nyuam muaj kev loj hlob hormone nrog cov cheeb tsam ntau tshaj, ces gigantism tsim, thiab cov neeg laus tsim acromegaly, txawm li ntawd los, thiab nrog gigantism, cov tsos mob ntawm acromegaly yog ua tau, tom qab kaw cov kab mob ntawm cov kab mob tau txais ib daim ntawv ntau dua.
Qis ntau tshaj qhov kev loj hlob hormone feem ntau ua rau txoj kev loj hlob ntawm tus me nyuam, tshwj xeeb tshaj yog nyob rau hauv cov txheej txheem uas ua rau kev ua haujlwm ntawm qhov hypothalamic-pituitary ib feem (pauv kev kis tus kab mob rau hauv lub cev, mob hawb pob). Gigantism hauv qhov teeb meem no yog tsim los tsis hais hnub nyoog li cas, tiam sis feem ntau qhov kev tsuj zuj zus tuaj rau hauv cov me nyuam hauv preschool los yog lub hnub nyoog kawm ntawv. Cov me nyuam yaus yooj yim fatigued, lawv tsis ua hauj lwm rau cov kab mob qis dua, tus mus ua tsis zoo tsim, nrog kev ntsuam xyuas ceev nrooj koj tuaj yeem pom cov acromegaloid qhov kev ua tau zoo, thiab lub incongruity ntawm daim duab tau pom.
Tsis tshua muaj ntau yam pituitary gigantism. Qhov ua rau kev loj hlob ntawm pituitary gigantism feem ntau yog eosinophilic adenoma, tsawg zaus nrog ib lub qog ntawm hypothalamus.
Qee zaum, acromegaly thiab gigantism pib ua hypothalamic ntshawv siab ua rau hyperplasia thiab hypertrophy, uas tuaj yeem ua rau cov qog hlob zoo li kev loj hlob ntawm somatotropic hlwb. Nyob rau hauv ib tug xov tooj ntawm cov neeg mob nyob rau hauv pubertal lub sij hawm nws ua tau pom tseeb tias tus me nyuam tau ceev nrawm, tab sis qee zaus nws tuaj yeem pom muaj hnub nyoog tsib xyoos. Yog li ntawd, txoj kev loj hlob tuaj yeem ncav cuag 250 lossis ntau tshaj ib xees.
Feem ntau cov me nyuam loj hlob tsis loj hlob yog tau los ntawm cov menyuam yaus uas muaj kev sib daj sib deev ntxov, tab sis lawv tsis dhau los ua cov loj loj, vim yog qhov kaw ntxov ntawm kev loj hlob aav (tom qab kaw, kev loj hlob nres).
Cov neeg mob siab tsis siab kho mob siab, tsis muaj tus kabmob hypoconadism, thyrotoxicosis, thiab cov neeg mob nrog arachnodactyly (Marfan syndrome) yog cov tsos mob ntawm cov kab mob ntawm cov kab mob, cov neeg mob xws li qis ntawm kev loj hlob zoo li qub.
Qhov ua rau kev txhim kho ntawm tus mob Clinfelter syndrome yog chromosomal aberration nrog tus kuaj X X chromosome. Nyob rau hauv cov tub hluas uas muaj siab ntev ntev thiab ob txhais tes thaum yau, ib lub cev tsis muaj zog, thiab tom qab tsim kev rog. Tus mob ntawm Clainfelter muaj qhov txawv txaij - hypoplasia ntawm chaw mos thiab noob qes. Cov kev sib deev theem ob yog kev ua tsis tau zoo, qee zaum muaj gynecomastia, cov plaub hau kis tau los ntawm cov poj niam duab.
Hauv cov neeg mob, muaj kev lag luam hauv kev puas siab puas ntsws, qhov no piav qhia los ntawm ib qho ntxiv X chromosome.
Sotos syndrome (cerebral gigantism), tsis zoo li pituitary gigantism, tshwm sim ntau dua, thiab nrog kev loj hlob sai, tab sis nyob rau hauv cov ntshav siab ntawm qib somatotropin seem tsis txaus, thiab cov ntaub ntawv qhia tau hais tias qhov ua rau pathology yog hlwb mob.
Thoob plaws 4-5 xyoos tus me nyuam loj hlob sai, ces tus me nyuam rov zoo dua qub. Lub sijhawm pubertal pib ntxov me ntsis lossis hauv cov lus sib txawv. Nyob rau hauv xws li cov neeg mob, muaj cov loj taw thiab txhuam nrog ib tug tuab txheej ntawm subcutaneous rog. Muaj kev puas hlwb hauv txoj kev loj hlob. Lub taub hau ntawm dolichocephalic daim ntawv loj loj, lub puab tsaig sab hauv qab mus rau pem hauv ntej, kev taug kev yog clumsy, lub qhov muag muaj dav spaced, tus neeg mob yog clumsy, kev tswj ntawm taw yog cuam tshuam.